EC Gastroenterology and Digestive System

Case Report Volume 10 Issue 6 - 2023

Intestinal Microbiota Transplantation and Clostridiodes difficile. A Relevant Case

Álvaro Zamudio Tiburcio1*, Héctor Bermúdez Ruiz2, Silverio Alonso López3, Pedro Antonio Reyes López4 and Martín Julián Carrillo5

1Department of Gastroenterology, Intestinal Microbiota Transplantation Medical Specialties Naples Unit, Mexico

2Endoscopy Service, Oncology Hospital, National Medical Center, XXI Century, Mexican Social Security. Institute, Hospital Trinidad, Mexico City, Mexico

3Department of Urologist, Chairman Medical Specialties Naples in Mexico City, Mexico

4Immunologist, Rheumatologist, National Institute of Cardiology “I. Chávez”, Mexico City, Mexico

5Critical Medicine. Hospital Trinidad, Mexico City, Mexico

*Corresponding Author: Álvaro Zamudio Tiburcio, Department of Gastroenterology, Intestinal Microbiota Transplantation Medical Specialties Naples Unit, Mexico.
Received: June 19, 2023; Published: June 27, 2023



After delving into numerous articles and having our own history of successful intestinal microbiota transplantation (IMT), we were fortunate that a new patient was referred, with pseudomembranous colitis; on this occasion, Clostridiodes difficile covered the entire colon.

The patient, 75 years old, and the history that her husband had died of sepsis caused by the same bacterium, and a series of co-morbidities, which are explained in their corresponding place.

The first transplant was performed one week after the onset of diarrhea, due to failure with antibiotic therapy, using fecal microbiota of less than 8 hours of preparation, and given the severe findings, we point out the need for a new colon exploration, in not more than 72 hours. This was carried out a week later, where, surprisingly, we observed that the enormous amount of C. difficile had disappeared, leaving only minimal lesions in the rectum, for which reason we performed a second IMT, following the total cure of the pathological process.

Keywords: Intestinal Microbiota Transplantation (IMT); Clostridiodes difficile (CD); Intestinal Microbiota (IM); Probiotics, Prebiotics and Symbiotics (BIOT)

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Álvaro Zamudio Tiburcio., et al. "Intestinal Microbiota Transplantation and Clostridiodes difficile. A Relevant Case". EC Gastroenterology and Digestive System  10.6 (2023): 01-06.