EC Gastroenterology and Digestive System

Case Report Volume 12 Issue 3 - 2026

Imaging Features of Primary Hepatic Melanoma: A Rare Hepatic Malignancy

Yahya Mokhlis1,2*, Sahar Ramdani1,2, Mohamed Fadil1,2, Asaad El Bakkari1,2, Youssef Omor1,2, Rachida Latib1,2, Fatimazahrae Laamrani1,2, Sanae Amalik1,2, El Mehdi Bouayad1,3 and Ismail Boujida1,3

1Mohammed V University, Rabat, Morocco
2Radiology Department, The National Institute of Oncology, University Hospital Ibn Sina, Rabat, Morocco
3Anatomical Pathology Department, The National Institute of Oncology, University Hospital Ibn Sina, Rabat, Morocco
*Corresponding Author: Yahya Mokhlis, Radiology Department, The National Institute of Oncology, University Hospital Ibn Sina, Rabat, Morocco.
Received: June 05, 2026; Published: June 11, 2026



Melanoma is a malignant tumor that primarily arises at the dermoepidermal junction or within melanocyte-rich tissues, including the skin, mucous membranes, as well as certain ocular structures (ciliary body, iris, choroid) and the meninges. Although the liver is a common site of metastatic spread for melanoma, primary hepatic melanoma remains exceedingly rare, with only a limited number of cases reported in the literature. The diagnosis of primary hepatic melanoma remains challenging due to the lack of specific clinical and radiological features, and it is a diagnosis of exclusion, because the liver is usual site of melanoma metastasis, the diagnosis is based on radiological exams that include ultrasound, Ct scan, MRI, the definitive diagnosis is based on histology, therefore a biopsy will be indicated. It is usually asymptomatic, when symptoms occur, they manifest by right upper quadrant abdominal pain, hepatomegaly, Unin- tentional weight loss, nausea.

 Keywords: Primary Hepatic Melanoma; Melanocytes; Primary Tumor of Liver; Non-Cutaneous Melanoma

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Yahya Mokhlis., et al. “Imaging Features of Primary Hepatic Melanoma: A Rare Hepatic Malignancy”. EC Gastroenterology and Digestive System 12.3 (2025): 01-09.

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