EC Gastroenterology and Digestive System

The complexity of human diseases is increasing dynamically with change in environment, diet and life style. The human gut microbiome, a vast community of microorganisms residing in the gastrointestinal tract, has emerged as a fascinating area of research in recent years. Composed of trillions of bacteria, viruses, fungi, and other microorganisms, the gut microbiome plays a crucial role in maintaining human health. The present research focuses on exploring the intricate relationship between the gut microbiome and various aspects of human well-being, shedding light on its influence on digestion, immune function, mental health, and overall systemic balance [1].

Digestive health and gut microbiome

The gut microbiome has significant impact on the process of digestion and nutrient absorption. Beneficial bacteria residing in the gut assist in the breakdown of complex carbohydrates, fibres, and other indigestible components, producing short-chain fatty acids (SCFAs) as by-products [2]. SCFAs provide an energy source for intestinal cells, stimulate the production of mucus, and enhance the absorption of minerals. Moreover, the gut microbiome plays a vital role in the metabolism of bile acids and vitamins, such as biotin, folate, and vitamin K, further emphasizing its impact on digestive health. Identifying the digestive health supporting gut microbiome is an active window of research and development.

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