EC Emergency Medicine And Critical Care

Cade oil, also known as Katran oil, is widely used in traditional Moroccan medicine for its antiseptic and parasiticidal properties. However, it has been associated with serious or fatal toxicity, especially in children. We report a case of a 12-month-old male infant who presented with severe systemic toxicity after exposure to cade oil applied to his scalp and extremities by his grandmother to treat fever and diarrhea. The infant developed generalized convulsive seizures, acute renal failure, and liver cytolysis. Brain MRI revealed anoxo-ischemic lesions in bilateral cortico-subcortical areas of the cerebellar hemispheres, cerebellar peduncles, posterior part of the Pons, and some frontal and parietal gyrus. The infant survived after symptomatic treatment and was discharged after seven days of hospitalization. This case highlights the potential dangers of cade oil and underscores the need to raise public awareness of its toxic effects.

 Keywords: Cade Oil; Katran Oil; Multi-Visceral Toxicity; Acute Renal Failure; Liver Cytolysis; Brain MRI; Anoxo-Ischemic Lesions

1. Belakhdar J. “La pharmacopée marocaine traditionnelle, médecine arabe ancienne et savoirs populaires”. Paris: Ibis Press (1997).
2. S Benomar., et al. “Connaissances et pratiques traditionnelles des mères en matière de soins des nouveaux-nés”. Archives de pédiatrie 7 (2000): 713-789.
3. I Teixidor-Toneu., et al. “Treating infants with frigg: linking disease aetiologies, medicinal plant use and care-seeking behaviour in southern Morocco”. Journal of Ethnobiology and Ethnomedicine 1 (2017): 4.
4. ST Koruk., et al. “Juniper tar poisoning”. Clinical Toxicology (Phila)1 (2005): 47-49.
5. A Sanae., et al. “Intoxication mortelle à l’huile de cade à propos de deux cas”. Urgence Prat (2008).
6. Skalli S., et al. “Side effects of cade oil in Morocco: an analysis of reports in the Moroccan herbal products database from 2004 to 2012”. Food and Chemical Toxicology 64 (2014): 81-85.
7. Rahmani H., et al. “Severe acute lung oedema after rectal enema with cade oil”. Clinical Toxicology 42 (2004): 395-564.