EC Dental Science

Erdheim Chester disease emerges as an exceptionally discerned, clonal disorder demonstrating infiltration of histiocytic cells within various tissues and frequent involvement of multiple organs. Initially scripted by William Chester and Jakob Erdheim in 1930, the condition is additionally designated as polyostotic sclerosing histiocytosis. The disorder was contemplated to be an inflammatory disease and carried a preceding nomenclature of lipoid (cholesterol) granulomatosis. With the current World Health Organization (WHO) classification of tumours of Haematopoietic and Lymphoid Tissues 2016, the disorder is categorized within ‘L’ group of revised histiocytic disorders classification.

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10. Image1 Courtesy: Frontiers.com.
11. Image 2 Courtesy: Pathology outlines.