Department of Histopathology, Panjab University, A.B. Diagnostics, India
Myoepithelial carcinoma of salivary gland emerges as a carcinoma constituted of myoepithelial cells in entirety or demonstrating an almost comprehensive population of myoepithelial cells. Myoepithelial carcinoma of salivary gland exhibits an infiltrative pattern of tumour growth.
Tumefaction may arise de novo or as myoepithelial carcinoma ex pleomorphic adenoma. Generally, myoepithelial carcinoma appears as an under-reported entity. Additionally, the terminology of malignant myoepithelioma appears debatable and non advocated.
Comprehensively composed of myoepithelial cells, myoepithelial carcinoma of salivary gland is devoid of a contemporary, well defined grading system.
Salivary gland myoepithelial carcinoma is subcategorized as myoepithelial carcinoma de novo or myoepithelial carcinoma ex pleomorphic adenoma. An estimated > 50% neoplasms exhibit PLAG1 genetic fusion.
Anubha Bajaj. "The Transitioned Slabber-Myoepithelial Carcinoma-Salivary Gland". EC Dental Science 22.7 (2023): 74-78.
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