EC Dental Science

Background: Advancements in regenerative medicine have significantly transformed the landscape of oral surgery and implantology, ushering in an era where biological enhancement of healing processes is not only possible but increasingly standard. One of the most promising innovations in this regard is the use of Concentrated Growth Factors (CGFs)-an autologous, platelet-rich material obtained through specific centrifugation protocols. CGFs contain a rich matrix of growth factors, platelets, leukocytes, and cytokines, all of which synergistically contribute to accelerated wound healing, enhanced angiogenesis, improved osseointegration, and reduced postoperative complications. Their role has become particularly relevant in immediate implantology, a technique in which dental implants are placed directly into extraction sockets, often within the same surgical visit.

Objective: This article aims to present a comprehensive analysis of the biological functions, clinical protocols, and therapeutic potential of CGFs, particularly in the context of immediate implant placement and broader oral surgical procedures. It discusses how CGFs serve not only as a biological scaffold but also as a powerful healing modulator that can influence hard and soft tissue regeneration. By reviewing contemporary literature and synthesizing clinical insights, this work offers both theoretical and practical frameworks for implementing CGFs into modern dental practice.

 Keywords: Concentrated Growth Factors (CGFs); Immediate Implantology; Oral Surgery; Platelet-Rich Fibrin (PRF); Platelet-Rich Plasma (PRP); Bone Regeneration; Soft Tissue Healing; Osseointegration; Autologous Biomaterials; Angiogenesis; Socket Preservation; Sinus Lift; Regenerative Dentistry; Growth Factor Therapy

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