EC Dental Science

Primary central nervous system lymphoma (PCNSL) is an uncommon variant of brain tumour devoid of concurrent systemic disease upon initial disease discernment, thereby demarcating the condition from central nervous system incriminated with secondary, systemic lymphoma.

Majority (> 90%) of the exceptional, aggressive primary central nervous system lymphomas arise as B cell lymphomas, especially diffuse large B cell lymphoma and high grade Burkitt-like B cell lymphoma. Malignant cells preferentially circumscribe and infiltrate vascular articulations. Low grade neoplasms emerge as T cell lymphoma or low grade B cell lymphoma.

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5. Image 1 Courtesy: Radiopaedia.com.
6. Image 2 Courtesy: Wikimedia commons.com.