EC Dental Science

Regenerative medicine is one of the fastest-growing fields in healthcare, leading to innovation and the development of new treatments for various diseases. In Dentistry, multiple types of stem cells can be used to regenerate different anatomical features and enhance the success of current therapies. This literature review explores the most recent applications of dental pulp stem cells (DPSCs) in Dentistry by reviewing various academic articles on PubMed.

The results reveal that DPSCs have multiple uses, such as regenerating pulpal tissues and applications in treating systemic illnesses. DPSCs can also restore new vascular structures, aiding in angiogenesis and maintaining homeostasis. In endodontics, DPSCs can regenerate pulpal tissues subcutaneously. Moreover, its applications enhanced the regeneration of various tissues, blood vessels, and neurogenesis. Alternatively, in periodontics, DPSCs reduced the inflammatory responses of periodontal tissues. When combined with a Bio-Oss xenograft, DPSCs enhanced the regeneration rate for PDL and cementum. These findings suggest further research to investigate the capacity for DPSCs use in Dentistry.

Keywords: Regenerative Medicine; Dental Pulp Stem Cells (DPSCs); Dentistry; Bio-Oss Xenograft

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