Department of Histopathology, Panjab University, A.B. Diagnostics, India
CIC rearranged sarcoma configures as an undifferentiated, small round cell soft tissue sarcoma with capicua-double homeobox 4 (CIC-DUX4) genetic fusion. The extremely exceptional, high grade, aggressive CIC rearranged sarcoma emerges as an undifferentiated small round cell sarcoma demonstrating CIC genetic fusions, commonly a CIC-DUX4 genomic fusion.
Clinical representation, histological countenance, immunological profile, molecular characteristics and genetic signature of CIC rearranged sarcoma is diverse from Ewing sarcoma and associated tumours. However, appropriate discernment of confirmatory molecular genomic fusion of CIC gene is necessitated. The sarcoma preponderantly incriminates paediatric subjects or young adults.
Anubha Bajaj. "Teensy and Orbed-CIC Rearranged Sarcoma Teensy and Orbed-CIC Rearranged Sarcoma". EC Dental Science 22.7 (2023): 01-05.
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