EC Dental Science

Severe mosquito bite allergy manifests as an uncommon cutaneous manifestation of natural killer (NK) cell subtype of chronic active Epstein Barr viral (CAEBV) infection. Predominantly documented in Japan, severe mosquito bite allergy characteristically delineates hypersensitivity to mosquito bites.

Severe mosquito bite allergy is designated as an Epstein Barr virus (EBV+) induced NK cell lymphoproliferative disorder and represents as a cutaneous variant of chronic active Epstein Barr virus (CAEBV) infection. Severe mosquito bite allergy characteristically denominates an exaggerated allergic reaction to mosquito bites, incriminates diverse cutaneous surfaces and demonstrates a prolonged clinical course. Severe mosquito bite allergy is accompanied by complications such as hemophagocytic lymphohistiocytosis (HLH), hydroa vacciniforme-like lymphoproliferative disorder or systemic chronic active Epstein Barr virus (CAEBV) infection. Besides, enhanced possible emergence of overt NK/T cell lymphoma or aggressive NK cell leukaemia is encountered. The exceptionally discerned severe mosquito bite allergy predominantly incriminates Asians or Japanese.

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7. Image 1 Courtesy: Semantic scholar.
8. Image 2 Courtesy: ASH.com.