EC Dental Science

Myxofibrosarcoma is constituted of an amalgamation of malignant fibroblastic tumours pervaded with myxoid stroma and characteristic curvilinear vascular articulations. Neoplastic cellular component exhibits variable cellular and nuclear pleomorphism. Tumefaction may be alternatively scripted as myxoid malignant fibrous histiocytoma. Myxofibrosarcoma configures as a commonly discerned sarcoma occurring within elderly subjects and manifests as a painless, superficial, subcutaneous tumefaction predominantly confined to extremities.

Essentially, tumefaction appears as a multinodular, gelatinous, lobulated mass with an infiltrative perimeter.

Tumour is composed of spindle shaped cells, stellate cells and pleomorphic cells enmeshed within a myxoid stroma imbued with curvilinear vascular articulations. High grade, hyper-cellular neoplasms exhibit severe cellular and nuclear pleomorphism.

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6. Image 1 Courtesy: Pathology outlines.
7. Image 2 Courtesy: Semantic scholar.