EC Dental Science

Introduction: This work describes the current state of research on the role of salivary proteins in dental caries which causes irreversible damage in dental tissues. To date, no evidence is comprehensively proving that salivary proteins could serve as potential indicators for early diagnosis of the risk factors which lead to dental caries.

Aim of the Work: This review article aims to clarify the correlation between salivary proteins and dental caries.

Methodology: This review is comprehensive research of PuBMED and Google Scholar from the year 1979 to 2023.

Conclusion: The maintenance of oral health and protection from tooth erosion is one of the most important functions of human saliva. Salivary proteins play an essential role in maintaining oral health and dentition intact. Several studies have investigated the correlation between these proteins and dental caries occurrence. The relationship between a protein or group of proteins and the occurrence of dental caries were mentioned in a few studies and most of these results are controversial. As a multifunctional disease, associating caries with only one risk factors is probably not promising and a more complex association should be sought.

 Keywords: Salivary Protein; Dental Caries; Oral Health

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