EC Dental Science

Editorial Volume 22 Issue 3 - 2023

Premalignant and Ambiguous- Fibroepithelioma of Pinkus

Anubha Bajaj*

Department of Histopathology, Panjab University, A.B. Diagnostics, India

*Corresponding Author: Anubha Bajaj, Department of Histopathology, Panjab University, A.B. Diagnostics, India.
Received: January 24, 2023; Published: February 09, 2023


Fibroepithelioma of Pinkus was initially scripted in 1953 by Dr Hermann Pinkus and is an uncommon, premalignant, cutaneous epithelial neoplasm originally cogitated as an exceptional variant of basal cell carcinoma [1]. Currently, a controversy exists whether fibroepithelioma of Pinkus is a variant of basal cell carcinoma or a trichoblastoma. Aforesaid lesions are engendered from follicular epithelial stem cells discerned within the bulge area of hair follicle. Follicular stem cells further enunciate follicular germinative cells or trichoblasts which generate the components of folliculo- sebaceous- apocrine unit in its entirety [1]. Trichoblasts which engender trichoblastoma and basal cell carcinoma exemplify common epithelial keratins and differentiate towards outer hair root sheath along with companion layer of the hair follicle. Follicular cells which express hair keratins engender hair fibre whereas follicular cells manifesting adjunctive varieties of keratin generate the inner root sheath [1,2].

Anubha Bajaj. “Premalignant and Ambiguous- Fibroepithelioma of Pinkus”.”. EC Dental Science 22.3 (2023): 01-10.