EC Dental Science

Review Article Volume 22 Issue 3 - 2023

Papillon-Lefèvre Syndrome: Prevalence and Characteristics in the Kingdom of Saudi Arabia

Hamzah Babkair1, Ismail Abdouh1*, Basem Akily1, Hattan Zaki2, Rahaf Almukhlifi3, Amaal Alroithi4 and Abdulrahman Alsani3

1Assistant Professor at Department of Oral Basic and Clinical Sciences, College of Dentistry, Taibah University, Al Madinah Al Munawara, Saudi Arabia
2Associate Professor at Department of Oral Basic and Clinical Sciences, College of Dentistry, Taibah University, Al Madinah Al Munawara, Saudi Arabia
3General Dentist, College of Dentistry, Taibah University, Al Madinah Al Munawara, Saudi Arabia
2Associate Professor at Department of Oral Basic and Clinical Sciences, College of Dentistry, Taibah University, Al Madinah Al Munawara, Saudi Arabia
4Saudi board Oral and Maxillofacial Surgery Resident-Ministry of National Guard Health Affairs – King Abdul-Aziz Medical City – Jeddah

*Corresponding Author: Ismail Abdouh, Assistant Professor at Department of Oral Basic and Clinical Sciences, College of Dentistry, Taibah University, Al Madinah Al Munawara, Saudi Arabia.
Received: February 18, 2023; Published: February 27, 2023



Objectives: The aim of the present review is to determine the prevalence and manifestations of reported cases of Papillon-Lefèvre Syndrome (PLS) in Saudi Arabia.

Methods: Pubmed and MEDLINE. Were combed through for relevant data includes any cases reported and published in Saudi Arabia were collected. Review of the associated factors and clinical manifestations of the reported cases of Papillon-Lefèvre Syndrome (PLS) were determined.

Results: The Papillon-Lefèvre Syndrome (PLS) is seen not uncommon with its prevalence rate in KSA. Age ranged from 3 - 19 years old with a mean of 10.33 years. Male constitutes 66.7% of the sample. The diagnosis of oral manifestations is challengeable and periodontal disease may represent mild form associated with cathepsin C gene mutation and allelic variations.

Conclusion: Although it is considered very rare syndrome, the number of reported cases in Saudi Arabia is not uncommon and this highlight the need for all dental health care providers to emphasize on its diagnostic and treatment modalities in the regional dental schools and clinical practice to establish a precise and definitive diagnosis and enhance the dental care services provided towards this group of patients.

Keywords: Papillon-Lefèvre Syndrome; Prevalence; Oral Manifestation; Oral Health

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Ismail Abdouh., et al. “Papillon-Lefèvre Syndrome: Prevalence and Characteristics in the Kingdom of Saudi Arabia”.”. EC Dental Science 22.3 (2023): 96-113.

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