EC Dental Science

Editorial Volume 24 Issue 10 - 2025

Osteo-Odonto-Keratoprosthesis (OOKP): A Visionary Integration of Dentistry and Ophthalmology

Arpit Sikri1* and Jyotsana Sikri2

1Associate Professor and Post Graduate Teacher, Department of Prosthodontics, Crown and Bridge and Oral Implantology, Bhojia Dental College and Hospital, Budh (Baddi), Himachal Pradesh, India

2Associate Professor and Post Graduate Teacher, Department of Conservative Dentistry and Endodontics, Bhojia Dental College and Hospital, Budh (Baddi), Himachal Pradesh, India

*Corresponding Author: Arpit Sikri, Associate Professor and Post Graduate Teacher, Department of Prosthodontics, Crown and Bridge and Oral Implantology, Bhojia Dental College and Hospital, Budh (Baddi), Teh. Baddi, Distt. Solan, Himachal Pradesh, India.
Received: July 24, 2025; Published: September 23, 2025



In the realm of ocular surface reconstruction, few procedures exemplify the convergence of surgical innovation and interdisciplinary collaboration as remarkably as the osteo-odonto-keratoprosthesis (OOKP). Developed in the mid-20th century, OOKP stands as a testament to the ingenuity of combining dental tissue with ophthalmic prosthetics, offering a final beacon of hope for patients suffering from end-stage bilateral corneal blindness-particularly when conventional keratoplasty or other artificial corneal implants are bound to fail.

  1. Falcinelli G., et al. “Modified osteo-odonto-keratoprosthesis for treatment of corneal blindness: long-term anatomical and functional outcomes in 181 cases”. Archives of Ophthalmology 10 (2005): 1319-1329.
  2. Liu C., et al. “The osteo-odonto-keratoprosthesis (OOKP)”. Seminars in Ophthalmology 2 (2005): 113-128.
  3. Tan A., et al. “Osteo-odonto-keratoprosthesis: Systematic review of surgical outcomes and complications”. Ocular Surface 1 (2012): 15-25.
  4. Liu C., et al. “Visual rehabilitation in end-stage inflammatory ocular surface disease with the osteo-odonto-keratoprosthesis: results from the UK”. British Journal of Ophthalmology 9 (2008): 1211-1217.
  5. Iannetti L., et al. “Clinical outcomes in osteo-odonto-keratoprosthesis patients with long-term follow-up”. Graefe's Archive for Clinical and Experimental Ophthalmology 8 (2011): 1155-1160.
  6. Ramaesh K and Dhillon B. “Ex vivo expansion of corneal epithelial cells”. British Journal of Ophthalmology 4 (2003): 379-384.
  7. Dua HS and Said DG. “Contemporary indications and techniques of keratoprosthesis surgery”. British Journal of Ophthalmology2 (2017): 118-124.
  8. Riau AK., et al. “Cultivation of stem cells for regenerative therapy: a review”. Molecular Vision 17 (2011): 2526-2540.

Arpit Sikri and Jyotsana Sikri. “Osteo-Odonto-Keratoprosthesis (OOKP): A Visionary Integration of Dentistry and Ophthalmology”. EC Dental Science  24.10 (2025): 01-03.

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