EC Dental Science

Erythrodermic cutaneous T cell lymphoma (CTCL) is constituted of primary cutaneous lymphomas which manifest erythroderma such as Sézary syndrome and erythrodermic mycosis fungoides.

Sézary syndrome is defined as a leukemic variant of cutaneous T cell lymphoma (CTCL) demonstrating erythroderma, generalized lymphadenopathy and clonal T cell proliferation. Clonal, neoplastic T cells are imbued with cerebriform nuclei (Sézary cells) and may disseminate within cutaneous surfaces, regional lymph nodes and peripheral blood.

1. Roccuzzo G., et al. “Sézary Syndrome: Different Erythroderma Morphological Features with Proposal for a Clinical Score System”. Cells3 (2022): 333.
2. Jonak C., et al. “Mycosis fungoides and Sézary syndrome”. Journal der Deutschen Dermatologischen Gesellschaft9 (2021): 1307-1334.
3. Vakiti A., et al. “Sézary Syndrome”. Stat Pearls International, Treasure Island, Florida (2022).
4. Snowden C Ng S., et al. “Partial remission of advanced untreated Sézary syndrome after COVID-19”. JAAD Case Reports 21 (2022): 165-168.
5. Image 1 Courtesy: Plastic surgery key.
6. Image 2 Courtesy: Springer link.