Case Report Volume 25 Issue 3 - 2026

Facial Volume Replacement with Poly-L-Lactic Acid: A Case Report

Márcio Macedo Soares1* and Renato Macedo Soares2

1Dentist in a Private Practice in Rio de Janeiro, Brazil
2Associate Professor in Estácio de Sá University, Department of Dental Prosthesis and Dentist in a Private Practice in Rio de Janeiro, Brazil

*Corresponding Author: Márcio Macedo Soares, Dentist in a Private Practice in Rio de Janeiro, Brazil.
Received: January 23, 2026; Published: March 10, 2026



Introduction: Poly-l-lactic acid has been used for cosmetic purposes in the United States, since 2004, for the treatment of human immunodeficiency virus lipoatrophy. This paper aims to present one case report and our experience with the use of poly-l-lactic acid for the cosmetic purpose of restoring facial volume lost due to the aging process.

Methods: Case report of female patient, seventy years old, were treated in private practice between 2020 and 2021. The product was reconstituted in 16 ml of distilled water and mixed with 2 ml of xylocaine 2% whithout epinephrine at the time of injection. Individualized treatment was performed according to each patient facial size and contour. The result was analyzed through photographs taken before and after surgery as well as subjective evaluations made by the cirurgian and patients.

Results: The patient was satisfied with the results. Adverse effects included of ecchymosis at the injection site, swelling and nothing nodules in the regions.

Conclusion: Poly-l-lactic acid can be used safely for restoring, correcting, and smoothing facial deformities arising from aging.

Keywords: Cosmetic Techniques; Face; Skin Aging; Lactic Acid

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Márcio Macedo Soares and Renato Macedo Soares. “Facial Volume Replacement with Poly-L-Lactic Acid: A Case Report”. EC Den- tal Science 25.3 (2026): 01-06.