EC Dental Science

Research Article Volume 22 Issue 7 - 2023

Evaluation of Blood Type and Oral Microbial Prevalence Suggests Potential Modulation of Selenomonas noxia but not Scardovia wiggsiae by Oral Antibodies: A Pilot Study

Tyler Pisciotta1, Robert Schwartz1 and Karl Kingsley2*

1Third-Year Dental Student in the Department of Clinical Sciences at the University of Nevada, Las Vegas - School of Dental Medicine, Las Vegas, Nevada, USA
2Professor of Biomedical Sciences at the University of Nevada, Las Vegas - School of Dental Medicine, Las Vegas, Nevada, USA

*Corresponding Author: Karl Kingsley, Professor of Biomedical Sciences at the University of Nevada, Las Vegas - School of Dental Medicine, Las Vegas, Nevada, USA.
Received: June 01, 2023; Published: June 13, 2023

Introduction: The goal of this project was to screen an existing saliva biorepository to determine patient blood type (A, B, AB, O) for potential correlations with the presence (or absence) of oral microbial pathogens, including Scardovia wiggsiae (SW), Selenomonas noxia (SN), Porphyromonas gingivalis (PG), and Streptococcus mutans (SM).

Methods: A total of n = 50 samples from an existing saliva repository were screened for A-B-O blood groups revealing 58% were blood type O, 32% were blood type A, 10% were blood type B and none were blood type AB, which was not significantly different from the overall distribution of blood groups in the overall population (52.6%, 29.4%, 15.8%, 3.2%, respectively), p = 0.3652.

Results: All samples were screened for the presence of SW, SN, PG and SM, revealing 100% of SN-positives were among the A- (75%) and B- (25%) blood groups with no SN positive samples found among the O- (0%) blood group, p = 0.0629. PG-positives were equally split mostly between the O- (50%) and A- (50%) blood group with no PG-positive samples among the B- blood group (0%), p = 0.5290. In contrast, SM-positives were found among patients with A- (64%) B- (21%) and O- (14%) blood types, p = 0.6566. with SW-positives found among patients with O- (55%), A- (27%) and B- (18%) type blood, p = 0.6584.

Conclusion: These data suggest host modulation of the oral microbiome by anti-A and -B antibodies, which may affect both SN and PG periodontal pathogens. Both cariogenic pathogens SM and SW were mostly found among the O-blood group, suggesting anti-A and anti-B antibodies had limited or no specific effects. These data may represent one of the first studies to determine whether blood types and the resulting oral antibodies may be associated with oral prevalence of the newly characterized periodontal and cariogenic pathogens Selenomonas noxia and Scardovia wiggsiae, specifically.

Keywords: Saliva Screening; Oral Microbial Pathogens; ABO Blood Groups; Oral Microbiome

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Karl Kingsley., et al. "Evaluation of Blood Type and Oral Microbial Prevalence Suggests Potential Modulation of Selenomonas noxia but not Scardovia wiggsiae by Oral Antibodies: A Pilot Study". EC Dental Science 22.7 (2023): 06-17.