EC Dental Science

Aggressive NK cell leukaemia (ANKL) is an exceptional disorder simulating morphological and genetic features of extra-nodal NK/T cell lymphoma or diverse natural killer (NK) cell malignancies although an acute clinical representation and aggressive biological course may segregate the malignancy from various NK cell neoplasms. Cogent disease discernment is challenging and the condition demonstrates an unfavourable prognosis.

Aggressive NK cell leukaemia can be appropriately detected with pertinent morphological and immuno-phenotypic manifestations. Incrimination of bone marrow may be preponderant or subtle. Although cytological atypia is significant, a subset of neoplasms may be configured of bland neoplastic cells.

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7. Image 1 Courtesy: Science direct.
8. Image 2 Courtesy: ASH.com.