Editorial Volume 24 Issue 12 - 2025

Contagion and Defilement-Yersinia pestis Lymphadenitis

Anubha Bajaj*

Department of Histopathology, Panjab University, A.B. Diagnostics, India

*Corresponding Author: Anubha Bajaj, Department of Histopathology, Panjab University, A.B. Diagnostics, India.
Received: November 10, 2025; Published: November 27, 2025



Bacterial infection with gram negative Yersinia pestis is associated with mesenteric lymphadenitis. Infected individual demonstrates clinical symptoms simulating acute appendicitis and a probable abdominal mass. The condition is self limiting although concurrence with Kawasaki’s disease is observed.

  1. Dillard RL and Juergens AL. “Plague”. Stat Pearls International. Treasure Island, Florida (2025).
  2. Sheneman KR., et al. “Yersinia pestis actively inhibits the production of extracellular vesicles by human neutrophils”. Journal of Extracellular Vesicles 4 (2025): e70074.
  3. Brady MF., et al. “Yersinia pseudotuberculosis”. Stat Pearls International. Treasure Island. Florida (2025).
  4. Fava P., et al. “Cutaneous B-cell lymphomas: Update on diagnosis, risk-stratification, and management”. La Presse Médicale 1 (2022): 104109.
  5. Grygiel-Górniak B. “Current challenges in Yersinia diagnosis and treatment”. Microorganisms 5 (2025): 1133.
  6. Aziz M and Yelamanchili VS. “Yersinia enterocolitica”. Stat Pearls International. Treasure Island, Florida (2025).
  7. Demeure CE., et al. “Yersinia pestis and plague: an updated view on evolution, virulence determinants, immune subversion, vaccination, and diagnostics”. Genes and Immunity 5 (2019): 357-370.
  8. Bosio CF., et al. “Evidence of a role for the F1 capsule of Yersinia pestis in enhancing transmission from mammals to fleas in a mouse model of bubonic plague”. mBio5 (2025): e0030125.
  9. Bland DM., et al. “Acquisition of yersinia murine toxin enabled Yersinia pestis to expand the range of mammalian hosts that sustain flea-borne plague”. PLoS Pathogens10 (2021): e1009995.
  10. Spyrou MA., et al. “Analysis of 3800-year-old Yersinia pestis genomes suggests Bronze Age origin for bubonic plague”. Nature Communications 1 (2018): 2234.
  11. Image 1 Courtesy: Pathology outlines.
  12. Image 2 Courtesy: Wikidoc.com.

Anubha Bajaj. “Contagion and Defilement-Yersinia pestis Lymphadenitis”. EC Dental Science  24.12 (2025): 01-04.