EC Dental Science

Review Article Volume 23 Issue 3 - 2024

Chilled Solutions: Cryotherapy’s Impact on Periodontics

Arjun MR1, Anil Melath2, Nanditha Chandran1, Paventhan Jolie Coeur3*, Fathimathul Fahada4 and Fathimathu Fiza4

1Reader, Mahe Institute of Dental Sciences and Hospital, Mahe, India
2Professor and HOD, Mahe Institute of Dental Sciences and Hospital, Mahe, India
3Post Graduate, Mahe Institute of Dental Sciences and Hospital, Mahe, India
4Undergraduate, Mahe Institute of Dental Sciences and Hospital, Mahe, India

*Corresponding Author: Paventhan Jolie Coeur, Post Graduate, Mahe Institute of Dental Sciences and Hospital, Mahe, India.
Received: February 16, 2024; Published: March 08, 2024



This comprehensive review delves into the multifaceted applications of cryotherapy in periodontics, focusing on its mechanisms, historical evolution, and clinical efficacy. Cryotherapy, utilizing intense cold to purposefully destroy tissue, emerges as a promising avenue in periodontal care, particularly in procedures such as gingival depigmentation and addressing specific conditions. The historical overview traces its roots from ancient cold therapies to modern cryosurgery techniques, showcasing its evolution and widespread adoption in medical and dental fields. The mechanisms of action highlight its effectiveness through reduced blood flow, metabolic activity, and neural inhibition, making it a virtually painless procedure. The review explores cryotherapy techniques, including open and closed systems, providing insights into controlled tissue freezing. In gingival depigmentation, cryotherapy proves valuable in achieving aesthetically pleasing results, with potential advantages over traditional techniques. A comparative analysis of cryotherapy methods in gingival hyperpigmentation treatment reveals varying outcomes, necessitating further research for a comprehensive understanding. The review also explores cryotherapy's applications beyond pigmentation, such as in managing localized juvenile spongiotic gingival hyperplasia and gum enlargement in Sturge-Weber syndrome patients. Despite drawbacks like unpredictable swelling, cryotherapy stands out as a valuable, patient-friendly tool in periodontics, offering non-invasive alternatives for various dental procedures. The abstract encapsulates the review's emphasis on cryotherapy's potential advancements, effectiveness, and versatility in periodontal treatment.

 Keywords: Cryotherapy; Periodontics; Gingival Depigmentation; Cryosurgery; Dental Support Structures; Mechanisms of Action; Comparative Analysis; Hyperpigmentation Treatment; Cryogenic Temperature Chamber; Cryogens; Joule-Thomson Principle; Gingival Plastic Surgery; Pediatric Periodontics; Sturge-Weber Syndrome; Tissue Freezing; Aesthetic Concerns; Non-Invasive Dentistry

  1. Farah CS and Savage NW. “Cryotherapy for treatment of oral lesions”. Australian Dental Journal 1 (2006): 2-5.
  2. Krishnan S M R M., et al. “Liquid nitrogen cryotherapy in the management of hemangioma of the tongue”. Cureus5 (2022): e24683.
  3. Anusre A., et al. “Cryotherapy in dentistry - A review”. International Journal of Research Publication and Reviews12 (2022): 213-219.
  4. Yadav VS., et al. “Cryotherapy as a conservative treatment modality for gingival enlargement in a patient with Sturge-Weber Syndrome”. Intractable and Rare Diseases Research 2 (2017): 145-1147.
  5. Prasad SS., et al. “Gingival depigmentation: A case report”. People's Journal of Scientific Research 1 (2010): 27-29.
  6. Narayankar SD., et al. “Comparative evaluation of gingival depigmentation by tetrafluroethane cryosurgery and surgical scalpel technique. A randomized clinical study”. Contemporary Clinical Dentistry 1 (2017): 90-95.
  7. Kathariya R and Pradeep AR. “Split mouth de-epithelization techniques for gingival depigmentation: A case series and review of literature”. Journal of Indian Society of Periodontology 2 (2011): 161-168.
  8. Thangavelu A., et al. “Pink esthetics in periodontics - Gingival depigmentation: A case series”. Journal of Pharmacy and Bioallied Sciences 2 (2012): S186-S190.
  9. Grover HS., et al. “Evaluation of patient response and recurrence of pigmentation following gingival depigmentation using laser and scalpel technique: A clinical study”. Journal of Indian Society of Periodontology 5 (2014): 586-592.
  10. Penmetsa GS., et al. “Melanocyte response following depigmentation by cryosurgery and mucosal excision: A comparative clinical and histopathological study”. Contemporary Clinical Dentistry 2 (2019): 214-219.
  11. Hosadurga R., et al. “Oral repigmentation after depigmentation - A short review and case report”. Pigment International2 (2017): 112-114.
  12. Billingham RE. “Dendritic cells in pigmented human skin”. Journal of Anatomy 2 (1949): 109-115.
  13. Raut RB., et al. “Gingival pigmentation: Its incidence amongst the Indian adults”. JAIDA 26 (1954): 9-10.
  14. Penmetsa GS., et al. “Melanocyte response following depigmentation by cryosurgery and mucosal excision: a comparative clinical and histopathological study”. Contemporary Clinical Dentistry 2 (2019): 214-219.
  15. Jokar L., et al. “A comparison of 940 nm diode laser and cryosurgery with liquid nitrogen in the treatment of gingival physiologic hyperpigmentation using split mouth technique: 12 months follow up”. Journal of Lasers in Medical Sciences 2 (2019): 131-138.
  16. Darbandi A and Shahbaz NA. “Effect of cryotherapy on physiologic pigmentation of oral mucosa: a preliminary study”. Journal of Dentistry of Tehran University of Medical Sciences 2 (2004): 49-52.
  17. Shirazi ARS., et al. “Treatment of gingival physiologic pigmentation in adolescent using cryosurgery technique with liquid nitrogen: one year follow up”. Journal of Mashhad Dental School 4 (2010): 331-342.
  18. Nogueira VK., et al. “Cryotherapy for localized juvenile spongiotic gingival hyperplasia: preliminary findings on two cases”. International Journal of Paediatric Dentistry 3 (2017): 231-235.

Paventhan Jolie Coeur., et al. “Chilled Solutions: Cryotherapy’s Impact on Periodontics”.”. EC Dental Science 23.3 (2024): 01-06.