Case Report Volume 8 Issue 11 - 2025

Understanding Gamna-Gandy Bodies and its Imaging Aspects: A Case Report

Bouanane Rania*, Belkouchi Lina, Taibi Ouiam, Siham El Haddad, Nazik Allali and Latifa Chat

Department of Radiology, Children Hospital of Rabat, Faculty of Medicine and Pharmacy of Rabat, Morocco

*Corresponding Author: Bouanane Rania, Department of Radiology, Children Hospital of Rabat, Ibn Sina University Hospital, Mohamed Ben Abdellah Regragui, Al Irfane, Rabat, Morocco.
Received: August 27, 2025; Published: October 29, 2025



Gamna-Gandy bodies, also recognized as splenic siderotic nodules, are pathological formations within the spleen. These nodules result from hemorrhagic and necrotic processes in the spleen's red pulp, often consequent to increased blood pressure, particularly observed in cases of portal hypertension [1]. Yet, to date, literature on the MRI detection of splenic Gamna-Gandy bodies is sparse and not widely familiar.

This case report details the diagnostic imaging findings and clinical implications of Gamna-Gandy bodies in a 16-year-old patient with recurrent bacterial cholangitis, that has progressed to hepatic cirrhosis, evaluated for potential complications, including Caroli's disease.

 Keywords: Gamna Gandy Bodies; Spleen; Pediatric Imaging; Case Report

  1. Bhatt S., et al. “Gamna-Gandy bodies: sonographic features with histopathologic correlation”. Journal of Ultrasound in Medicine 12 (2006): 1625-1629.
  2. E Dias., et al. “A rare sign of portal hypertension”. Acta Gastro-Enterologica Belgica 2 (2022): 414-415.
  3. Yilmaz S., et al. “Education and imaging. Hepatobiliary and pancreatic: Gamna-Gandy bodies of the spleen”. Journal of Gastroenterology and Hepatology 5 (2007): 758.
  4. Ünsal NH., et al. “Evaluation of the splenic vein diameter and longitudinal size of the spleen in patients with Gamna-Gandy bodies”. Diagnostic and Interventional Radiology 3 (2006): 125-128.
  5. Dobritz M., et al. “Gamna-Gandy bodies of the spleen detected with MR imaging. A case report”. Magnetic Resonance Imaging 9 (2001): 1249-51.
  6. Varma D., et al. “Gamna-gandy bodies of the spleen in CML: a casual association-a case report”. Indian Journal of Pathology and Microbiology 1 (2004): 51-52.
  7. Lambertucci JR., et al. “Gamna-Gandy bodies in hepatosplenic Schistosomiatis mansoni”. Revista da Sociedade Brasileira de Medicina Tropical 41 (2008): 320-321.
  8. Roubidoux MA. "MR of the kidneys, liver and spleen in paroxysmal nocturnal hemoglobinuria”. Abdominal imaging 2 (1994): 168-173.
  9. Sagoh T., et al. “Gamna-Gandy bodies of the spleen: evaluation with MR imaging”. Radiology3 (1989): 685-687.
  10. Bernaerts A., et al. “Gamna-Gandy bodies”. Journal Belge de Radiologie 5 (2001): 202.
  11. Zhang J., et al. “Gamna-Gandy bodies of the spleen detected with susceptibility weighted imaging: maybe a new potential non-invasive marker of esophageal varices”. PLoS One1 (2013): e55626.
  12. Dobritz M., et al. “Gamna-Gandy bodies of the spleen detected with MR imaging: a case report”. Magnetic Resonance Imaging 9 (2001): 1249-1251.
  13. Yasuhara K., et al. “Study of diffuse hyperechoic spots in spleen caused by Gamna-Gandy nodules”. Japanese Journal of Medical Ultrasonics 13 (1986): 1097-1098.
  14. Chan YL., et al. “Diagnostic accuracy of abdominal ultrasonography compared to magnetic resonance imaging in siderosis of the spleen”. Journal of Ultrasound in Medicine 19 (2000): 543-547.

Bouanane Rania., et al. “Understanding Gamna-Gandy Bodies and its Imaging Aspects: A Case Report”. EC Clinical and Medical Case Reports  8.11 (2025): 01-04.