EC Clinical and Medical Case Reports

A 58-year-old white man with chronic renal failure, presented with tumoral calcinosis involving cervical spine, and both hips, manifesting as severe upper cervical pain, and hip movement limitation. CT scan revealed a periarticular calcified mass with no bone involvement at the level of the vertebrae cervical, and two calcified masses in both hips. The diagnosis was made based on the radiological appearance and subsequently confirmed by anatomopathological examination. Tumoral calcinosis is a rare benign disease, characterized by calcified deposits in periarticular tissues. Only five cases of tumoral calcinosis of the upper cervical spine have been reported in the literature, our case is the sixth. The pathogenesis is yet not well understood. Surgery remains the treatment of choice, and the prognosis is generally favorable. We aim to underline the role of radiology in diagnosing this entity with an accompanied review of the literature.

Keywords: Tumoral Calcinosis; Cervical Spine; Hips; CT Scan; Hemodialysis

1. Laasri K., et al. “A rare case of idiopathic tumoral calcinosis: Case report”. Radiology Case Reports11 (2022): 4350-4353.
2. Ludig T., et al. “Tumors of the soft tissues of the knee in childhood; Osteo-articulaire masse des tissus mous de genou. Imagerie des masses des tissus mous du genou chez l'enfant”. Feuillets de Radiologie 38 (1998).
3. El Khatib K., et al. “Calcinose pseudo-tumorale plantaire: Ā propos d’un cas et revue de la littérature”. Revue de Chirurgie Orthopédique et Réparatrice de L'appareil Moteur5 (2004): 471-474.
4. Ammar A., et al. “Tumoral calcinosis: a clinical and pathological study of 8 cases reported in Tunisia”. Revue de Chirurgie Orthopedique et Reparatrice de L'appareil Moteur3 (1994): 261-266.
5. Mathieu G., et al. “Calcinose tumorale idiopathique: À propos de deux cas et revue de la littérature”. Revue de Chirurgie Orthopédique et Réparatrice de L'appareil Moteur4 (2006): 358-363.
6. Fikri M., et al. “La calcinose tumorale à propos de deux cas pédiatriques". Journal of Radiology 88 (2007): 595-598.
7. En-Nafaa I., et al. “Tumoral calcinosis: A case report”. Archives de Pediatrie: Organe Officiel de la Societe Francaise de Pediatrie8 (2010): 1165-1168.
8. Polykandriotis EP., et al. “A case of familial tumoral calcinosis in a neonate and review of the literature”. Archives of Orthopaedic and Trauma Surgery 124 (2004): 563-567.
9. Huguet D., et al. “Tumoral calcinosis of the foot in patient on hemodialysis”. Revue de Chirurgie Orthopedique et Reparatrice de L'appareil Moteur3 (2000): 289-292.
10. El Houss S., et al. “Hyperphosphatemic familial tumoral calcinosis mimicking a cystic hemo-lymphangioma on MRI”. Radiology Case Reports12 (2022): 4603-4607.
11. Karibe H., et al. “Clinical characteristics and outcome in elderly patients with traumatic brain injury: for establishment of management strategy”. Neurologia Medico-Chirurgica8 (2017): 418-425.
12. Kokubun S., et al. “Tumoral calcinosis in the upper cervical spine: a case report”. Spine2 (1996): 249-252.
13. Mooney JF and Steven S Glazier. "Tumoral calcinosis of the cervical spine in an infant: Case illustration”. Journal of Neurosurgery1 (1997): 162-162.
14. Ohashi K., et al. “Idiopathic tumoral calcinosis involving the cervical spine”. Skeletal Radiology 25 (1996): 388-390.
15. Shaffrey CI., et al. “Tumoral Calcium Pyrophosphate Dihydrate Deposition Disease Mimicking a Cervical Spine NeoplasmCase Report”. Neurosurgery2 (1995): 335-339.
16. Brown ML., et al. “Radiography and scintigraphy in tumoral calcinosis”. Radiology3 (1977): 757-758.
17. Olsen KM., et al. “Tumoral calcinosis: pearls, polemics, and alternative possibilities”. Radiographics3 (2006): 871-885.
18. Chebbi W., et al. “Tumoral calcinosis: a rare disease”. La Tunisie Medicale2 (2021): 306-310.