EC Clinical and Medical Case Reports

POEMS syndrome is a lymphoproliferative disease, a paraneoplastic disorder. POEMS (polyneuropathy, organomegaly, endocrinopathy, M-protein and skin changes). Moreover its other important traits include sclerotic bone lesions, thrombocytosis, pappilloedema, clubbing, castlemans disease [1]. The radiological findings of bone lesions differ from those in myeloma in the sclerotic appearance of focal lesions [2,4]. In the majority of patients the diagnosis is confirmed by the identification of monoclonal plasma cells obtained through biopsy of an osteosclerotic lesion; as such, a whole-body X-ray survey is essential to detect focal lesions [5-7].

Keywords: POEMS Syndrome; POEMS (Polyneuropathy, Organomegaly, Endocrinopathy, M-Protein and Skin Changes); PET-CT

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