EC Clinical and Medical Case Reports

Pseudo lipomas of Glisson's capsule are rare, benign subcapsular liver lesions, typically found on the diaphragmatic surface of Glisson's capsule. They consist of degenerating fat, likely from epiploic appendages or traumatic fat cell inclusion after liver surgery. Most commonly seen in older men, these lesions are often asymptomatic and discovered incidentally on imaging. On CT scans, they appear as well-defined, round, hypodense nodules with fat attenuation. Histologically, they share features with epiploic appendages, including fat, fibrous tissue, and sometimes calcifications or inflammation. Differential diagnoses include serosal metastases, solitary necrotic nodules, focal steatosis, and hepatocellular carcinoma, with key distinguishing features being fat density and location on imaging. Treatment is rarely required, except in symptomatic cases, with an excellent prognosis and no malignant potential.

 Keywords: Pseudo Lipomas; Glisson's Capsule; Liver Lesion

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