EC Clinical and Medical Case Reports

Primary Hyperparathyroidism (PHPT) is a disease characterized by excessive secretion of parathyroid hormone (PTH), leading to the resorption of parts of the skeleton, bone loss and elevated calcium levels. Brown tumor (BT) aka Von Recklinghausen’s disease of bone is a rare skeletal manifestation of PHPT. This multiple benign bone lesion may simulate a metastatic bone disease, posing a great diagnostic challenge for the clinician. A high index of suspicion is needed for diagnosis in its early stage. Clinical suspicion, laboratory and radiological investigations are required to diagnose this condition. In a resource poor setting like ours, unavailability and unaffordability of these facilities, poses a greater challenge. We present a 39 year old lady with multiple bone lesions, initially considered to be a metastatic bone disease, but later turned out to be BT. In all cases, with multiple osteolytic lesions, a possibility of “BT” must be kept in mind.

Keywords: Primary Hyperparathyroidism; Brown Tumour; Metastatic Bone Disease

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