EC Clinical and Medical Case Reports

Gestational autoimmune liver disease (GALD) is now recognized as the major cause of neonatal hemochromatosis in almost all the cases. Cases of neonatal hemochromatosis due to gestational autoimmune liver disease can result in fetal demise, stillbirth or neonatal acute liver failure. Neonatal hemochromatosis due to GALD is not hereditary; rather it is congenital materno-fetal alloimmune disorder that results in fetal liver injury. This makes GALD a treatable and preventable disorder which underlines the importance of establishing a diagnosis early in order to provide the appropriate management.

 Keywords: GALD: Gestational Autoimmune Liver Disease; NH: Neonatal Hemochromatosis; IUGR: Intrauterine Growth Restriction; IVIG: Intravenous Immunoglobulin G

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