EC Clinical and Medical Case Reports

Review Article Volume 8 Issue 6 - 2025

Liquid Biopsy: Current Echelon and Future Outlooks

Amrita Satpathy1, Rajlaxmi Sarangi1, Sumit Jhajharia1, Tapaswini Pradhan1 and Jyoti Prakash Sahoo2*

1Biochemistry, Kalinga Institute of Medical Sciences, KIIT University, India

2Pharmacology, Kalinga Institute of Medical Sciences, KIIT University, India

*Corresponding Author: Jyoti Prakash Sahoo, Kalinga Institute of Medical Sciences, KIIT University, Bhubaneswar, Odisha, India.
Received: April 20, 2025; Published: May 19, 2025



A novel and non-invasive diagnostic technique called liquid biopsy has significant potential for detecting and tracking a number of ailments, including cancer, neurological disorders, cardiovascular conditions, and infectious diseases. Unlike conventional biopsy techniques, which necessitate intrusive procedures, liquid biopsy uses bodily fluid analysis-specifically, blood, urine, or saliva-to find biomarkers such as extracellular vesicles (EV), circulating tumour DNA (ctDNA), or microRNA (miRNA). Early identification, treatment response tracking, and minimal residual disease assessment are promising for the future, allowing for more individualised cancer treatment with fewer side effects. Through the identification of neurodegenerative biomarkers, liquid biopsy aids in the early diagnosis of Alzheimer's, Parkinson's, and other neurodegenerative disorders, allowing for earlier management, better treatment outcomes, and prognosis. The risk assessment and treatment choices can be made using liquid biopsy biomarkers for myocardial infarction, atherosclerosis, and heart failure. More efficient treatment strategies have been developed due to pathogen identification and liquid biopsy monitoring of illness progression. Because of its transformative approach, liquid biopsy is a superior substitute for conventional diagnostic techniques. It provides comprehensive and real-time insights into the course of a wide range of diseases, making it an essential tool in healthcare.

 Keywords: Liquid Biopsy; Cancer; Brain; Heart; Infection

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Jyoti Prakash Sahoo., et al. "Liquid Biopsy: Current Echelon and Future Outlooks." EC Clinical and Medical Case Reports 8.6 (2025): 01-10.