EC Clinical and Medical Case Reports

Background: Intracranial neurenteric cysts are rare congenital lesions arising from endodermal remnants misplaced during embryogenesis. They are mostly located in the posterior fossa or spinal canal and rarely found in supratentorial regions.

Case Presentation: We report the case of a 38-year-old woman presenting with chronic headaches. MRI demonstrated a well-defined, non-enhancing cystic lesion in the left parietal region, with characteristic T1 hypointensity, T2 hyperintensity, and partial suppression on FLAIR sequences. Findings were consistent with a neurenteric cyst.

Conclusion: Neurenteric cysts should be considered in the differential diagnosis of parietal cystic brain lesions. MRI remains the gold standard for characterization and surgical planning.

 Keywords: Neurenteric Cyst; Parietal Lobe; MRI; Intracranial Cyst; Adult

1. Osborn AG., et al. “Diagnostic Imaging: Brain”. 4^th Elsevier (2023).
2. Shroff M., et al. “Pediatric congenital cystic lesions of the brain: spectrum and imaging features”. Pediatric Radiology 3 (2024): 379-394.
3. Cheng Y., et al. “Intracranial neurenteric cysts: clinical, imaging, and surgical outcomes in a multicenter study”. Neurosurgery2 (2023): 301-310.
4. Shastri N., et al. “Role of MRI in the diagnosis and follow-up of intracranial neurenteric cysts”. Frontiers in Radiology 3 (2024): 1476234.
5. Biswas S., et al. “Embryologic basis and clinicopathologic correlations of neurenteric cysts”. Journal of Clinical Neuroscience 110 (2023): 76-83.
6. Wang H., et al. “Intracranial neurenteric cysts: A systematic review of 214 cases”. World Neurosurgery 167 (2022): e1178-e1188.
7. Kubota T., et al. “MRI features and long-term outcome of intracranial neurenteric cysts”. American Journal of Neuroradiology 1 (2024): 92-99.
8. Long B., et al. “Imaging differentiation of congenital intracranial cysts: a practical review”. Radiographics 2 (2025): 387-404.
9. Singh A., et al. “Diffusion-weighted MRI in differentiating epidermoid from neurenteric cysts”. Clinical Imaging 91 (2023): 17-22.
10. Li J., et al. “Surgical management and recurrence risk of intracranial neurenteric cysts: experience from 15 years”. BMC Neurology1 (2024): 156.