EC Clinical and Medical Case Reports

Terpenes, derived from various plant sources (Essential oil terpenes), exhibit diverse pharmacological properties and have been historically utilized in urolithiasis treatment. Early experiments demonstrated terpene efficacy in reducing urinary stone formation in animal models, while clinical studies underscored their tolerability and potential efficacy in human subjects. Mechanistic insights suggest renal hyperemia and antispasmodic effects as potential contributors to terpene-mediated stone dissolution and expulsion. However, challenges including the scarcity of controlled trials and mechanistic ambiguity persist, necessitating further research. Recent investigations have explored novel therapeutic approaches combining terpenes with traditional preventive therapies, yielding promising outcomes in pediatric urolithiasis management. Embracing innovative strategies may pave the way for improved clinical outcomes and enhanced understanding of terpene mechanisms in urolithiasis management.

The aim of this educational article is to explore the therapeutic potential of essential oil terpenes in the management of urolithiasis, a condition characterized by the formation of urinary tract stones.

 Keywords: Urolithiasis; Innovative Strategies; Essential Oil Terpenes

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