EC Clinical and Medical Case Reports

Review Article Volume 6 Issue 11 - 2023

Future Perspective of Hyssopus officinalis

Arifa Hassan1 and Mohd Rafi Reshi2*

1Department of Physiology, Govt. Medical College Udhampur, J & K, India

2Department of Pharmacology, Govt. Medical College Kathua, J & K, India

*Corresponding Author: Mohd Rafi Reshi, Demonstrator, Department of Pharmacology, Govt. Medical College Kathua, J & K, India.
Received: September 24, 2023; Published: October 17, 2023



Hyssopus officinalis L., commonly known as hyssop, jufa, zufah-yabis, and zufah in other languages, is a member of the Lamiaceae family. It is a perennial plant that is frequently grown in temperate regions of North America, Asia, and Europe. The health benefits and therapeutic uses of H. officinalis are typically based on tradition rather than any scientific validation, making it an excellent candidate for compiling data on phytochemical contents, traditional uses, and biological activities available in recent scientific studies. Iso Pino Camphone (5.3%), Pino Camphone (19.6%), Pino Carvone (36.3%), -pinene (10.6%), and 1,8-cineole (7.2%) were the main components. It provides a variety of pharmaceutical benefits, including anti-oxidant, anti-fungal, anti-microbial, anti-diabetic, anti-ulcer and anti-inflammatory characteristics.

 Keywords: Pharmacological Property; Constituents; Photochemistry

  1. Fathiazad F., et al. “Phytochemical analysis and antioxidant activity of Hyssopus officinalis from Iran”. Advanced Pharmaceutical Bulletin 1 (2011): 63-67.
  2. Ortiz De Elguea-Culebras G., et al. “Biocidal potential and chemical composition of industrial essential oils from Hyssopus officinalis, Lavandula x intermedia var. super, and Santolina chamaecyparissus”. Chemistry and Biodiversity 15 (2018): e1700313.
  3. Benelli G., et al. “Acute larvicidal toxicity of five essential oils (Pinus nigra, Hyssopus officinalis, Satureja montana, Aloysia citrodora and Pelargonium graveolens) against the filariasis vector Culex quinquefasciatus: synergistic and antagonistic effects”. Parasitology International Journal 66 (2017): 166-171.
  4. Kizil S., et al. “Blooming stages of Turkish hyssop (Hyssopus officinalis) affect essential oil composition”. Acta Agriculturae Scandinavica, Section B - Soil and Plant Science 58 (2008): 273-279.
  5. Zawislak G. “Hyssop herb yield and quality depending on harvest term and plant spacing”. Acta Scientiarum Polonorum Hortorum Cultus 10 (2011): 331-342.
  6. Mijani S., et al. “Seed germination and early growth responses of Hyssop, sweet basil, and oregano to temperature levels”. Notulae Scientia Biologicae 5 (2013): 462-467.
  7. Tabrizi L., et al. “Effect of biofertilizers on agronomic criteria of hyssop (Hyssopus officinalis)”. 2nd Conference of the International Society of Organic Agriculture Research ISOFAR (2008).
  8. Gorunovic MS. “Essential oil of Hyssopus officinalis, Lamiaceae of Montenegro origin”. Journal of Essential Oil Research 7.1 (1995): 39-43.
  9. Vallejo MCG., et al. “Volatile oil of Hyssopus officinalis from Spain”. Journal of Essential Oil Research 7.5 (1995): 567-568.
  10. Ben Hamida N. “Effect of salinity on the antiparasitic activity of hyssop essential oil”. Journal of Essential Oil Research 1 (2020): 69-78.
  11. Mićovic T. “Antioxidant, antigenotoxic and cytotoxic activity of essential oils and methanol extracts of Hyssopus officinalis Subsp. aristatus (Godr.) Nyman (Lamiaceae) Subsp. aristatus (godr.) nyman (lamiaceae)”. Plants 10.4 (2021): 711.
  12. Salehi B., et al. “Avocado-soybean unsaponifiables: a panoply of potentialities to be exploited”. Biomolecules1 (2020): 130.
  13. Garg S. “Composition of essential oil from an annual crop of Hyssopus officinalis grown in Indian plains”. Flavour and Fragrance Journal 3 (1999): 170-172.
  14. Shah NC. “Gas chromatographic examination of oil of Hyssopus officinalis”. Parfuemerie und Kosmetik 67 (1986): 116-118.
  15. Joulain D. “Study of the chemical composition of hyssop (Hyssopus officinalis Linnaeus) essential oil”. Rivista Italiana Essenze 58 (1976): 479-485.
  16. Ozer H., et al. “Essential oil composition of Hyssopus officinalis L. subsp. angustifolius (Bieb.) Arcangeli from Turkey”. Flavour and Fragrance Journal 1 (2005): 42-44.
  17. Höld KM., et al. “Metabolism and mode of action of cis- and trans-3- pinanones (the active ingredients of hyssop oil)”. Xenobiotica 4 (2002): 251-265.
  18. Benedec D. “The presence of the superior aliphatic acids in Hyssopus officinalis L,” (Lamiaceae)”. Farmacia-Bucuresti 50 (2002): 61-64.
  19. Chalchat JC., et al. “Composition of oils of three cultivated forms of Hyssopus officinalis Endemic in Yugoslavia: f. albus Alef., F. cyaneus Alef and f. ruber Mill”. Journal of Essential Oil Research 6 (2001): 419-421.
  20. Zawislak G. “Essential oil composition of Hyssopus officinalis grown in Poland”. Journal of Essential Oil-Bearing Plants 19.3 (2016): 699-705.
  21. Said-Al Ahl H. “Essential oil composition of Hyssopus officinalis cultivated in Egypt”. International Journal of Plant Research 1.2 (2015): 49-53.
  22. Ahmadi H., et al. “Effects of exogenous application of citrulline on prolonged water stress damages in hyssop (Hyssopus officinalis): Antioxidant activity, biochemical indices, and essential oils profile”. Food Chemistry 333.127433 (2020).
  23. Wang N and Yang XW. “Two new flavonoid glycosides from the whole herbs of Hyssopus officinalis”. Journal of Asian Natural Products Research 12 (2010): 1044-1050.
  24. Alinezhad H., et al. “Antioxidant and antihemolytic activities of ethanolic extract of flowers, leaves, and stems of Hyssopus officinalis L. var. angustifolius”. International Journal of Food Properties 16 (2013): 1169-1178.
  25. Fernandez-Lopez J., et al. “Evaluation of the antioxidant potential of Hyssop (Hyssopus officinalis ) and Rosemary (Rosmarinus officinalis L.) extracts in cooked pork meat”. Journal of Food Science 68 (2003): 660-664.
  26. Letessier MP., et al. “Antifungal activity of the essential oil of Hyssop (Hyssopus offcinalis)”. Journal of Phytopathology 149 (2001): 673-678.
  27. Fraternale D., et al. “Composition and antifungal activity of two essential oils of Hyssop (Hyssopus officinalis L)”. Journal of Essential Oil Research 16 (2004): 617-622.
  28. Ghfir B., et al. “Influence of essential oil of Hyssopus officinalis on the chemical composition of the walls of Aspergillus fumigatus (Fresenius)”. Mycopathologia 138 (1997): 7-12.
  29. Ortiz De Elguea-Culebras G., et al. “Biocidal potential and chemical composition of industrial essential oils from Hyssopus officinalis, Lavandula intermedia var. super, and Santolina chamaecyparissus”. Chemistry and Biodiversity 15 (2018): e1700313.
  30. Mazzanti G., et al. “Antimicrobial properties of the linalool-rich essential oil of Hyssopus officinalis var decumbens (Lamiaceae)”. Flavour and Fragrance Journal 13 (1998a): 289-294.

Arifa Hassan and Mohd Rafi Reshi. "Future Perspective of Hyssopus officinalis." EC Clinical and Medical Case Reports   6.11 (2023): 01-07.