EC Clinical and Medical Case Reports

Infection with the protozoan parasite Toxoplasma gondii occurs globally and it usually manifests no symptoms. However, a primary infection in a pregnant woman may spread to the fetus through the placenta [1]. An estimated 190,100 cases of congenital toxoplasmosis are reported worldwide each year, with an incidence of 1.5 occurrences per 1000 live births [2]. Chorioretinitis, cerebral calcifications, and hydrocephalus make up the classic triad of neonatal congenital toxoplasmosis, however they are rarely visible at birth [3]. Most newborns with congenital toxoplasmosis don't exhibit any symptoms. Here, we discuss a case in which prenatal and postnatal scans revealed complaints of hydrocephalus. The majority of the symptoms of this condition were surprisingly discovered in our instance. The maternal serology report, which was positive for Toxoplasma IgM, provided additional assistance with the diagnosis.

Keywords: Congenital Toxoplasmosis; Antenatal Scan; Toxoplasma gondii; Hydrocephalus; Toxoplasma IgM

1. Bollani L., et al. “Congenital Toxoplasmosis: The State of the Art”. Frontiers in Pediatrics 10 (2022): 894573.
2. Torgerson PR and Mastroiacovo P. “The global burden of congenital toxoplasmosis: a systematic review”. Bulletin of the World Health Organization 91 (2013): 501-508.
3. McLeod R., et al. “Management of Congenital Toxoplasmosis”. Current Pediatrics Reports3 (2014): 166-194.
4. Bollani L., et al. “Congenital toxoplasmosis”. Early Human Development 89 (2013): S70-S2.
5. Li J., et al. “One severe case of congenital toxoplasmosis in China with good response to azithromycin”. BMC Infectious Diseases1 (2021): 920.
6. Maldonado YA and Read JS. “Diagnosis, Treatment, and Prevention of Congenital Toxoplasmosis in the United States”. Pediatrics2 (2017).
7. Singh S. “Congenital toxoplasmosis: Clinical features, outcomes, treatment, and prevention”. Tropical Parasitology2 (2016): 113-122.
8. Osman M., et al. “Congenital toxoplasmosis the overlooked disease: a case report”. International Journal of Contemporary Pediatrics 8 (2021): 1107.
9. Konstantinovic N., et al. “Treatment of toxoplasmosis: Current options and future perspectives”. Food and Waterborne Parasitology 15 (2019): e00036.