EC Clinical and Medical Case Reports

Review Article Volume 7 Issue 5 - 2024

Concept, Etiopathogenesis and Management of Shaqeeqa (Migraine) in Greeco-Arabic System of Medicine

Mohammad Nasar K1*, Arzeena Jabeen2 and Majeeda Begum3

1Professor and HOD, Department of Molijat (General Medicine), National Research Institute of Unani Medicine for Skin Disorders, Hyderabad, TS, India

2Principal and Additional Director, National Research Institute of Unani Medicine for Skin Disorders, Hyderabad, TS, India

3Medical Officer, Dr. Abdul Haq Unani Medical College and Hospital, AP, India

*Corresponding Author: Mohammad Nasar K, Professor and HOD, Department of Molijat (General Medicine), National Research Institute of Unani Medicine for Skin Disorders, Hyderabad, TS, India.
Received: May 09, 2024; Published: May 20, 2024



Throughout history, Shaqeeqa (Migraine) has persisted as a formidable challenge, causing debilitating pain and disrupting the lives of those it afflicts. It is a recurring headache disorder with significant implications for individuals and society, presenting a considerable challenge. According to the Greeco Arabic System of Medicine or Unani System of Medicine "Su-e-Mizaj Maddi" plays a crucial role in migraine development. It is caused by morbid matters and vapors arising from imbalanced humors, with treatments focusing on eliminating these morbid substances and strengthening the brain. Conventional management relies on pharmacological and non-pharmacological methods, while traditional systems such as Unani medicine offer alternative treatments centered around balancing bodily humors and regimen therapies. This review explores Unani perspectives on migraine, including its etiology, classification based on temperament and location, triggers, and treatment modalities. Unani interventions encompass regimen therapy, wet cupping, hot irrigation, leech therapy, topical applications, and dietary adjustments. Although some Unani therapies show potential in reducing migraine frequency and intensity, further research is necessary to validate efficacy, elucidate mechanisms of action, and ensure safety. Integrating traditional medicine into comprehensive migraine management may provide complementary or alternative avenues, highlighting the need for rigorous clinical trials and integration with conventional medicine to offer efficacious and safe treatment.

 Keywords: Shaqeeqa; Migraine; Headache; Sue Muzaj Maddi; Unani Medicine

  1. Burstein R., et al. “Migraine: multiple processes, complex pathophysiology”. Journal of Neuroscience 17 (2015): 6619-6629.
  2. Vecchia D and Pietrobon D. “Migraine: a disorder of brain excitatory-inhibitory balance?” Trends in Neurosciences8 (2012): 507-520.
  3. Welch K. “Drug therapy of migraine”. New England Journal of Medicine 20 (1993): 1476-1483.
  4. Pietrobon D. “Migraine: New molecular mechanisms”. The Neuroscientist4 (2005): 373-386.
  5. Lipton RB and Bigal ME. “Migraine: Epidemiology, impact, and risk factors for progression”. Headache1 (2005): 3-13.
  6. Bigal ME., et al. “Age-dependent prevalence and clinical features of migraine”. Neurology2 (2006): 246-251.
  7. Gil‐Gouveia R., et al. “The impact of cognitive symptoms on migraine attack-related disability”. Cephalalgia 5 (2016): 422-430.
  8. Riyazuddin M., et al. “Migraine (Shaqeeqa) and its management in Unani medicine”. Drug Metabolism and Personalized Therapy (2021).
  9. Alam M., et al. “Understanding hormones in terms of humours (Akhlat) in Unani system of medicine”. Journal of Complementary and Integrative Medicine 3 (2020): 459-467.
  10. Faiz A., et al. “Holistic approach in unani system of medicine with respect to physis, humours and six essential factors”. Journal of Emerging Technologies and Innovative Research 3 (2019): 89-92.
  11. Lari QH and Wamiq MM. “Concept and Importance of Mizaj (temperament) in Unani System of Medicine”. Journal of Integrated Community Health 1 (2020): 8-12.
  12. Mohd A., et al. “A comprehensive review of Unani treatise elucidation of Shaqiqa (Migraine)”. Journal of Integrated Community Health 2 (2020): 11-14.
  13. Afzal U., et al. “Efficacy of Nutūl-i-Ḥār (Hot Irrigation), a Polyherbal Unani Formulation, in the Treatment of Shaqīqa-i-Muzmin (Chronic Migraine): An open single-arm exploratory clinical trial”. Traditional and Integrative Medicine 4 (2022): 34-37.
  14. , et al. “Management of migraine in a group of factory worker-prevalence study”. Journal of Epidemiology 23 (2018): 45-48.
  15. Mohd SA., et al. “Shaqeeqa (Migraine): Concept and management in Unani Medicine”. International Journal of Creative Research Thoughts 11 (2020): 3489-3493.
  16. Tai M., et al. “Geographical differences in trigger factors of tension-type headaches and migraines”. Current Pain and Headache Reports 2 (2019): 1-6.
  17. Kumaraswamy B., et al. “Migraine-A complete review”. The Pharma Innovation Journal 2 (2013): 135-143.
  18. Chakravarty A., et al. “Migraine pain location: how do children differ from adults?” The Journal of Headache and Pain 9 (2008): 375-379.
  19. Azhar M. “Adverse effect of Unani pharmacopeial formulation Habb-E-Shifa”. Journal of Pharmacovigilance4 (2018): 269.
  20. Zargaran A., et al. “A review on the management of migraine in the Avicenna’s Canon of Medicine”. Neurological Sciences3 (2016): 471-478.
  21. Usmani S. “Management of musculoskeletal disorder through Ilaj-bit-Tadbeer (Regimental Therapy) - A review”. Journal of Integrated Community Health2 (2021): 22-26.
  22. Ansari S., et al. “Post-auricular leech therapy reduced headache and migraine days in chronic migraine”. Journal of Drug Delivery and Therapeutics1 (2019): 75-80.
  23. Sah A., et al. “Design and development of a topical nanogel formulation comprising of a Unani medicinal agent for the management of pain”. Gels 10 (2023): 794.
  24. Ghazanfar K., et al. “Safety evaluation of Unani formulation: Capsule Shaqeeqa in Albino Wistar Rats”. Scientifica (2016): 2683403.
  25. Khoso D., et al. “Cupping therapy in the view of Islamic teaching”. Al Khadim Research Journal of Islamic Culture and Civilization (2022).

Mohammad Nasar K., et al. "Concept, Etiopathogenesis and Management of Shaqeeqa (Migraine) in Greeco-Arabic System of Medicine." EC Clinical and Medical Case Reports   7.5 (2024): 01-06.