EC Clinical and Medical Case Reports

Despite the efforts of doctors in many countries of the world aimed at controlling blood pressure (BP), the prevalence of arterial hypertension (AH) in populations of different countries continues to grow and by 2025 the total number of patients with this nosology will reach 1.5 billion [1]. The most urgent task of medical care for patients with hypertension is considered to be the reduction of cardiovascular risk [2]. This makes it necessary to develop new, more effective approaches to the diagnosis and treatment of hypertension. In order to treat patients with hypertension, two methods of therapy have been developed by the efforts of many scientists for decades: a) hypotensive and b) antihypertensive. The priorities of the appointment of basic therapy are due to complex clinical mechanisms of the formation and stabilization of hypertension, when it is necessary to use drugs that have a pathogenetic orientation (depending on which they are divided into different groups of pharmacological influence). In some clinical situations, it is possible to supplement basic

1. Clinical guidelines. Arterial hypertension in adults. All-Russian public organization. "Russian Society of Cardiology". Approved by the Scientific and Practical Council of the Ministry of Health of the Russian Federation (2020).
2. Böhm M., et al. “Achieved blood pressure and cardiovascular outcomes in high-risk patients: results from ONTARGET and TRANSCEND trials”. Lancet10085 (2017): 2226-2237.
3. Fan E., et al. “Recruitment maneuvers for acute lung injury: a systematic review”. American Journal of Respiratory and Critical Care Medicine11 (2008): 1156-1163.
4. 2019 ESC Guidelines for the diagnosis and management of acute pulmonary embolism developed in collaboration with the European Respiratory Society (ERS) (2019).