EC Clinical and Medical Case Reports

Mini Review Volume 6 Issue 8 - 2023

Atypical Clinical Manifestations of Hepatobiliary Pathology

Katyukhin VN* and Ilchishina TA

REAVIZ University, St. Petersburg, Russia

*Corresponding Author: Katyukhin VN, REAVIZ University, St. Petersburg, Russia.
Received: May 12, 2023; Published: July 24, 2023



The traditional classification of hepatobiliary pathology can be presented [1], based on the etiological and pathogenetic factors of its occurrence, with a division into six groups of diseases:

  1. Mainly functional disorders - dyskinesia, motor-tonic dysfunctions of the gallbladder (GI), bile ducts and sphincters. Regardless of the etiology, they are usually divided into hyper- and hypokinetic dysfunction of the gastrointestinal tract and dysfunction of the sphincter of Oddi. Primary dyskinesia is formed on unchanged structures of the biliary tract. Secondary dyskinesia develops against the background of abnormalities of the gastrointestinal tract and ducts, chronic cholecystitis and cholelithiasis (GI).
  2. Inflammatory diseases are cholecystitis, cholangitis and cholangiohepatitis.
  3. Metabolic diseases - GI, hemosiderosis, Konovalov-Wilson's disease, Gaucher's disease and others.
  4. Parasitic - giardiasis, opisthorchiasis and other infestations.
  5. Benign and malignant tumors.
  6. Structural anomalies (congenital malformations) - absence of the gastrointestinal tract, bifurcation, constriction, diverticula, hypoplasia, aplasia of the bile ducts.

Keywords: Gallbladder (GI); Hepatobiliary Pathology; Hypoplasia; Aplasia

  1. Fundamentals of hepatology (Editor A.O. Bueverov). Moscow. Publishing house "ABC-press" (2022): 408.
  2. Botkin SP. “Course of internal medicine clinic and clinical lectures”. Moscow: Medgiz 2 (1950): 467-505.
  3. Fairfield CJ., et al. “Gallstone Disease and the Risk of Cardiovascular Disease”. Scientific Reports1 (2019): 5830.
  4. Shabanzadeh DM., et al. “Screen-detected gallstone disease and cardiovascular disease”. European Journal of Epidemiology6 (2017): 501-510.
  5. Brawman-Mintzer O., et al. “Psychosocial characteristics and pain burden of patients with suspected sphincter of Oddi dysfunction in the EPISOD multicenter trial”. The American Journal of Gastroenterology 3 (2014): 436-442.
  6. Tsai MC., et al. “Increased Risk of Depressive Disorder following Cholecystectomy for Gallstones”. PLoS One6 (2015): e0129962.
  7. Fikree A and Byrne P. “Management of functional gastrointestinal disorders”. Clinical Medicine Journals 1 (2021): 44-52.
  8. Al Zoubi M., et al. “Largest case series of giant gallstones ever reported, and review of the literature”. International Journal of Surgery Case Reports 72 (2020): 454-459.
  9. Andrea C and Enzo A. “Cholesterol gallstones larger than 3 cm appear to be associated with gallbladder cancer”. Annals of Surgery3 (2016): e56.
  10. Alabi A., et al. “Incidental Gallbladder Cancer: Routine versus Selective Histological Examination After Cholecystectomy”. International Journal of Surgery1 (2021): e22-e25.
  11. Pichetshote N and Pimentel M. “An Approach to the Patient with Chronic Undiagnosed Abdominal Pain”. The American Journal of Gastroenterology5 (2019): 726-732.
  12. Lapina TL and Bueverov AO. “Bitterness in the mouth: interpretation of a gastroenterologist”. Clinical Perspectives of Gastroenterology, Hepatology (2013): 3.
  13. Drossman DA. “Functional gastrointestinal disorders: history, pathophysiology, clinical features, and Rome IV”. Gastroenterology 6 (2016): 1262-1279.
  14. Ivashkin VT and Mayev IV. “Clinical recommendations of the Russian Gastroenterological Association for the diagnosis and treatment of biliary dyskinesia”. Russian Journal of Gastroenterology, Hepatology, Coloproctology3 (2018): 63-80.
  15. Mohammad Z. “Liver Function in Novel Coronavirus Disease (COVID-19): A Systematic Review and Meta-Analysis”. Med Rxiv (2020).

Katyukhin VN and Ilchishina TA. "Atypical Clinical Manifestations of Hepatobiliary Pathology." EC Clinical and Medical Case Reports   6.8 (2023): 01-09.