Mini Review Volume 9 Issue 1 - 2026

Aloe-Emodin in Aloe Vera Extract for Beneficial Effects on Brain Health with Mild Dementia and Cognitive Impairment in Alzheimer’s Disease

A Yagi1* and A Mukaitani2

1Special Adviser of Japan Aloe Science Association (JASA), Japan

2President of JASA, Japan

*Corresponding Author: A Yagi, Special Adviser of Japan Aloe Science Association (JASA), Japan.
Received: September 22, 2025; Published: December 31, 2025



Beneficial neuroprotective effects on brain health of Aloe vera extract; mild dementia and cognitive impairment in Alzheimer’s disease were reported. Aloe emodin from Aloe vera extract, alleviates cognitive dysfunction in Alzheimer’s disease, and reduces damage to hippocampal neurons. Aloe emodin based therapeutics with mild dementia and cognitive impairment in Alzheimer’s disease for decreases attributed to protein aggregation was reported.

 Keywords: Aloe Vera Extract; Aloe Emodin; Alleviation of Cognitive Dysfunction; Alzheimer’s Disease in Mild Dementia and Cognitive; Decrease; Protein Aggregation

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A Yagi and A Mukaitani. “Aloe-Emodin in Aloe Vera Extract for Beneficial Effects on Brain Health with Mild Dementia and Cognitive Impairment in Alzheimer’s Disease”. EC Clinical and Medical Case Reports  9.1 (2026): 01-04.