EC Clinical and Medical Case Reports

Mini Review Volume 6 Issue 2 - 2023

A Great Hope from Plant Origin Bio-Organic Anti-HIV Agents: Safety, Bio-Efficacy and Protection Issues

Yashi Upadhyay1* and Ravi Kant Upadhyay2

1Department of Biotechnology, Deen Dayal Upadhyaya Gorakhpur University, Gorakhpur, India

2Department of Zoology, Deen Dayal Upadhyaya Gorakhpur University, Gorakhpur, India

*Corresponding Author: Yashi Upadhyay, Department of Biotechnology, Deen Dayal Upadhyaya Gorakhpur University, Gorakhpur, India.
Received: December 06, 2022; Published: January 30, 2023




Present article signifies anti-HIV potential of various plant natural products. Till the date thousands of green biochemicals have been isolated and tested against HIV in vitro. Most of them have been displayed inhibition of reverse transcriptase, protease, integrase enzyme activity. These are also fusion inhibitors, CCR5 antagonists showed gp 120 attachment inhibition activity in vitro models. There is an immense need to have most appropriate and highly effective biochemical drug as a single compound or combinatorial drug or a complex of organic and heterocyclic compound to suppress HIV progression in human cells. Medicinal plants are large depository of antiretroviral agents which could be used for treatment of sexually transmitted diseases. Present review article tries to explore new possibilities of HIV control by suggesting important plant natural products which can be used for discovery and design of new drug candidates.

Keywords: HIV; Anti-HIV Drugs; Attachment Inhibitor; Protease Inhibitors; Replication Inhibitors; Anti-HIV Antibodies; Immunity Boosters

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Yashi Upadhyay and Ravi Kant Upadhyay. A Great Hope from Plant Origin Bio-Organic Anti-HIV Agents: Safety, Bio-Efficacy and Protection Issues. EC Clinical and Medical Case Reports   6.2 (2023): 38-45.

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