1Human Milk Research Laboratory, Department of Pharmacology, Universidad de Guadalajara, University Center of Exact Sciences and Engineering, Guadalajara, Jalisco, México
2Neonatology Service, Division of Pediatrics, O.P.D. Hospital Civil de Guadalajara "Fray Antonio Alcalde", Guadalajara, Jalisco, México
3Child Growth and Development, Pediatrics Specialty, Department of Human Reproduction Clinics, Universidad de Guadalajara, University Health Sciences Centre, Guadalajara, Jalisco, México
Introduction: Bartter Syndrome (BS) is a genetic kidney disorder that can be diagnosed at birth and affects 1 in 1,000,000 inhabitants. BS is characterized by losses of minerals such as sodium, potassium, or chloride through urine. This disease considers five different subtypes that are determined by the site of mutation in the gene. Patients with BS must have adequate medical treatment in addition to emphasizing the importance of a diet that supports the restitution of minerals lost due to the disease.
Case: We present the case of a 21-month-old female infant diagnosed with disorders resulting from renal tubular function, heart murmur, severe protein-calorie malnutrition with frequent dehydration, and Bartter syndrome type III. At the beginning of her consultations, the patient weighed 2.86 kg, length of 52 cm and the following biochemical evaluation: platelets 439,500/μl (142,000-424,000), urea 124 mg/dl (15-39), serum creatinine 0.31 mg/dl (0.50-1.20), phosphorus 5.1 mg/dl (2.7-4.5), serum calcium 12.5 mg/dl (8.4-10.2), chlorine 68 mmol/l (98-107), potassium 3.04 mmol/l (3.50-5.10) and sodium 146 mmol/l (135-145). The patient was fed comfort milk formula + powdered human milk, as a result, her weight and length increased (4.56 kg and 62 cm). The results of the biochemical evaluation were: platelets 229,600/μl (142,000-424,000), urea 96 mg/dl (15-39), serum creatinine 1.3 mg/dl (0.50-1.20), phosphorus 4.1 mg/dl (2.7-4.5), serum calcium 11.4 mg/dl (8.4-10.2), chlorine 86 mmol/l (98-107), potassium 2.9 mmol/l (3.50-5.10) and sodium 136 mmol/l (135-145).
Conclusion: BS is a pathological entity that causes multiple alterations at the renal, hydro electrolytic, hemodynamic, nutritional, and developmental levels, in addition to leading to frequent hospital stays. Feeding powdered human milk can be part of the dietary strategy for this type of patient.
Keywords: Bartter Syndrome; Human Milk Powder; Milk Formula; Dehydration;Diet
Anahí Castellanos-Haro., et al. "A Case Report: Beneficial Effect of Powder Human Milk in an Infant with Bartter Syndrome." EC Clinical and Medical Case Reports 7.10 (2024): 01-11.
© 2024 Anahí Castellanos-Haro., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
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