EC Clinical and Medical Case Reports

Multiple myeloma (MM) belongs to hematological malignancy that derives pro-survival/ proliferative signals from the bone marrow niche. Butyrate, a class I histone deacetylase inhibitor in MM, reduces the viability of MM cells, induces MM cell apoptosis via transcriptional activation of p21. The author discussed fermented butyrate in aloe vera juice (AVJ) as a potential adjuvant for MM, and in case reports of MM patient we expressed how autologous peripheral blood stem cell (APBST) transplantation therapy, and daratumab, velcade and dexamethasone (Dvd) and thalidomide administration recovered MM and how butyrate fermented in AVJ as an adjuvant prevented MM patient receiving paraneoplastic cerebella degeneration (PCD) treatment.

Keywords: Remission of Multiple Myeloma; APBST-Treatment; Drug Admission; Aloe Vera Gel; Fermented Butyrate; Case Reports

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