EC Anaesthesia

Research Article Volume 5 Issue 4 - 2019

Comparison of Electrical Cardiometry and Transoesophageal Doppler for Haemodynamic Monitoring during Living Donor Liver Transplantation: A Randomized Controlled Trial

Eman Sayed Ibrahim1*, Nagwa Ibrahem Mowafy2, Nagwa Mohamed Doha3, Ashraf Mohamed Mustafa4 and Khaled Ahmed Yassen5

1Assistant Professor of Anaesthesia and ICU, Liver Institute, Menoufia University, Shebeen Elkom, Egypt
2Lecturer of Anesthesia and ICU, Liver Institute, Menoufia University, Shebeen Elkom, Egypt
3Assistant Professor of Anaesthesia and ICU, Menoufia University, Shebeen Elkom, Egypt
4Professor of Anaesthesia and ICU, Menoufia University, Shebeen Elkom, Egypt
5Professor of Anaesthesia and ICU, Liver Institute, Menoufia University, Shebeen Elkom, Egypt

*Corresponding Author: Eman Sayed Ibrahim, Assistant Professor of Anaesthesia and ICU, Liver Institute, Menoufia University, Shebeen Elkom, Egypt.
Received: February 19, 2019; Published: March 28, 2019



Background: Cardiac output (CO) can be calculated noninvasively with Electrical Cardiometry (EC) utilizing thoracic electrical bioimpedance or minimal invasively with Transesophageal Doppler (TED). Aim was to compare EC to TED regarding (CO), ability to guided fluid administration and monitor haemodynamics during transplantation.

 Methods: 47 adult recipients (3 excluded): EC gp, (n = 22) and TED gp (n = 22). Following anaesthesia, TED probe was passed orally into mid-esophagus. Cardiometry skin sensors were applied simultaneously. In EC gp Anaesthetist were blinded to TED and vice versa. 6 ml/kg/h Ringer’s acetate, only 3 ml/kg Albumin 5% boluses when stroke volume variation (SVV) (%) in EC > 10% or corrected flow time (FTc) (msec) in TED < 350 msec. Rotational thromboelastometry guided blood products.

Results: Comparable age, weight, graft body weight ratio. An overall good degree of reliability between EC and TED CO, r = 0.928, 95% CI (0.913 - 0.941), p < 0.001. Median (IQR) EC CO was constantly higher than TED CO (l/min). After induction 7.55 [6.70 - 8.50] vs. 6.80 [6.10 - 7.50], p < 0.001, anhepatic: 7.60 [7.20 - 8.50] vs. 6.75 [6.35 - 7.50], p < 0.001, reperfusion: 7.90 [7.10 - 8.60] vs.7.25 [6.50 - 7.85] p < 0.001, end surgery 8.40 [8.00 - 8.80] vs.7.70 [7.25 - 8.20] p < 0.001, respectively. In EC vs. TED. 5500 [5200 - 6000] vs. 5525 [5200 - 6000] ml, p = 0.81 of Crystalloids and 800 [600 - 1000] vs. 850 [800 - 1000] ml, p = 0.2 of Albumin 5% were infused, respectively. FTc negatively correlated with SVV (t) = -0.321, p < 0.001, and both not in correlation with CVP.

Conclusion: The agreement between CO measured by EC and TED is acceptable. Both were able to monitor trend changes and guide fluid administration.

Keywords: Electrical Cardiometry; Transoesophageal Doppler; Liver Transplantation

  1. Mona Rezai Rudnick., et al. “Haemodynamic monitoring during liver transplantation: A state of the art review”. World Journal of Hepatology 10 (2015): 1302-1311.
  2. Amy C Robertson and Susan S Eagle. “Transesophageal echocardiography during orthotopic liver transplantation: maximizing information without the distraction”. Journal of Cardiothoracic and Vascular Anesthesia 1 (2014): 141-154.
  3. Schumann R. “Intraoperative resource utilization in anaesthesia for liver transplantation in the United States: a survey”. Anesthesia and Analgesia 1 (2003): 21-28.
  4. Ozier Y and Klinck JR. “Anaesthetic management of hepatic transplantation”. Current Opinion in Anesthesiology 3 (2008): 391-400.
  5. Bukowicka B., et al. “The occurrence of postreperfusion syndrome in orthotopic liver transplantation and its significance in terms of complications and short-term survival”. Annals of Transplantation2 (2011): 26-30.
  6. De Waal., et al. “Cardiac output monitoring”. Current Opinion in Anaesthesiology1 (2009): 71-77.
  7. Monsel A., et al. “The transesophageal doppler and haemodynamic effects of epidural anesthesia in infants anesthetized with sevoflurane and sufentanil”. Anesthesia and Analgesia 1 (2007): 46-50.
  8. Monnet X., et al. “Measuring aortic diameter improves accuracy of oesophageal doppler in assessing fluid responsiveness”. Critical Care Medicine 2 (2007): 477-482.
  9. De Waal EE., et al. “Assessment of stroke volume index with three different bioimpedance algorithms: lack of agreement compared to thermodilution”. Intensive Care Medicine 4 (2008): 735-739.
  10. Zoremba N., et al. “Comparison of electrical velocimetry and thermodilution techniques for the measurement of cardiac output”. Acta Anaesthesiologica Scandinavica 10 (2007): 1314-1319.
  11. Randhir Singh Rajput., et al. “Comparison of cardiac output measurement by noninvasive method with electrical cardiometry and invasive method with thermodilution technique in patients undergoing coronary artery bypass grafting”. World Journal of Cardiovascular Surgery7 (2014): 123-130.
  12. Saner FH., et al. “Delicate balance of bleeding and thrombosis in end-stage liver disease and liver transplantation”. Digestion 3 (2013): 135-144.
  13. Benes J., et al. “Intraoperative fluid optimization using stroke volume variation in high risk surgical patients: results of prospective randomized study”. Critical Care 3 (2010): R118.
  14. Sinclair S., et al. “Intraoperative intravascular volume optimisation and length of hospital stay after repair of proximal femoral fracture: randomised controlled trial”. British Medical Journal 7113 (1997): 909-912.
  15. El Sharkawy OA., et al. “Transoesophageal doppler compared to central venous pressure for perioperative haemodynamic monitoring and fluid guidance in liver resection”. Saudi Journal of Anaesthesia 4 (2013): 378-386.
  16. Nissen P., et al. “Techniques of cardiac output measurement during liver transplantation: arterial pulse wave versus thermodilution”. Liver Transplantation 3 (2009): 287-291.
  17. Spiess BD., et al. “Bioimpedance haemodynamics compared to pulmonary artery catheter monitoring during orthotopic liver transplantation”. Journal of Surgical Research 1 (1993): 52-56.
  18. Hussien M., et al. “Use of transesophageal doppler as a sole cardiac output monitor for reperfusion haemodynamic changes during living donor liver transplantation: An observational study”. Saudi Journal of Anaesthesia 3 (2011): 264-269.
  19. Schoenfeld D., et al. “Pulmonary-artery versus central venous catheter to guide treatment of acute lung injury”. New England Journal of Medicine 21 (2006): 2213-2224.
  20. Zöllner C., et al. “Continuous cardiac output measurements do not agree with conventional bolus thermodilution cardiac output determination”. Canadian Journal of Anesthesia 11 (2001): 1143-1147.
  21. Mihm FG., et al. “A multicenter evaluation of a new continuous cardiac output pulmonary artery catheter system”. Critical Care Medicine 8 (1998): 1346-1350.
  22. Vishwas Malik., et al. “Correlation of electric cardiometry and continuous thermodilution cardiac output monitoring systems”. World Journal of Cardiovascular Surgery 7 (2014): 101-108.
  23. Knirsch W., et al. “Comparison of cardiac output measurement using the Cardio Q oesophageal doppler with cardiac output measurement using thermodilution technique in children during heart catheterization”. Intensive Care Medicine 6 (2008): 1060-1064.
  24. Møller-Sørensen H., et al. “Transesophageal doppler reliably tracks changes in cardiac output in comparison with intermittent pulmonary artery thermodilution in cardiac surgery patients”. Journal of Clinical Monitoring and Computing1 (2017): 135-142.
  25. Ashraf M Moustafa., et al. “Electrical cardiometry compared to transoesophageal doppler for perioperative haemodynamic monitoring and fluid management in pediatrics undergoing kasai operation”. American Society of Anesthesiologists (2017).
  26. Lorne E., et al. “Accuracy of impedance cardiography for evaluating trends in cardiac output: a comparison with oesophageal Doppler”. British Journal of Anaesthesia 4 (2014): 596-602.
  27. Tibby SM., et al. “Use of transesophageal doppler ultrasonography in ventilated pediatric patients: derivation of cardiac output”. Critical Care Medicine 6 (2000): 2045-2050.
  28. Murdoch IA., et al. “Continuous haemodynamic monitoring in children: use of transoesophageal Doppler”. Acta Paediatrica 7 (1995): 761-764.
  29. Green DW. “Comparison of cardiac outputs during major surgery using the Deltex CardioQ oesophageal Doppler monitor and the Novametrix-Respironics NICO: a prospective observational study”. International Journal of Surgery 3 (2007): 176-182.
  30. Moira McKendry., et al. “Randomized controlled trial assessing the impact of a nurse delivered, flow monitored protocol for optimization of circulatory status after cardiac surgery”. British Medical Journal 329 (2004): 258.
  31. Chew MS and Poelaert J. “Accuracy and repeatability of pediatric cardiac output measurements using Doppler: 20-year review of the literature”. Intensive Care Medicine 11 (2003): 1889-1894.
  32. Neurinda P Kusumastuti and Masaki Osaki. “Electric velocimetry and transthoracic echocardiography for noninvasive cardiac output monitoring in children after cardiac surgery”. Critical Care and Shock 18 (2015): 36-42.
  33. Blohm ME., et al. “Impedance cardiography (electrical velocimetry) and transthoracic echocardiography for non-invasive cardiac output monitoring in pediatric intensive care patients: a prospective single-center observational study”. Critical Care 6 (2014): 603.
  34. Schmidt C., et al. “Comparison of electrical velocimetry and transoesophageal doppler echocardiography for measuring stroke volume and cardiac output”. British Journal of Anaesthesia5 (2005): 603-610.
  35. Magliocca A., et al. “Cardiac output measurements based on the pulse wave transit time and thoracic impedance exhibit limited agreement with thermodilution method during orthotopic liver transplantation”. Anesthesia and Analgesia 1 (2018): 85-92.
  36. Heringlake M., et al. “Lack of agreement between thermodilution and electrical velocimetry cardiac output measurements”. Intensive Care Medicine 12 (2007): 2168-2172.
  37. van der Meer BJ., et al. “PM Impedance cardiography: importance of the equation and the electrode configuration”. Intensive Care Medicine 10 (1996): 1120-1124.
  38. Van der Meer BJ., et al. “Impedance cardiography in cardiac surgery patients: abnormal body weight gives unreliable cardiac output measurements”. Acta Anaesthesiologica Scandinavica 6 (1997): 708-712.
  39. Jiang GQ., et al. “Individualized peri-operative fluid therapy facilitating early phase. recovery after liver transplantation”. World Journal of Gastroenterology 16 (2012): 1981-1986.
  40. Calvo-Vecino JM., et al. “Effect of goal-directed haemodynamic therapy on postoperative complications in low-moderate risk surgical patients: a multicentre randomized controlled trial”. British Journal of Anaesthesia 4 (2018): 734-744.
  41. Peng K., et al. “Goal-Directed fluid therapy based on stroke volume variations improves fluid management and gastrointestinal perfusion in patients undergoing major orthopedic surgery”. Medical Principles and Practice 5 (2014): 413-420.
  42. Srivastava D., et al. “Effect of intraoperative transesophageal Doppler guided fluid therapy versus central venous pressure guided fluid therapy on renal allograft outcome in patients undergoing living donor renal transplant surgery: a comparative study”. Journal of Anaesthesia 6 (2015): 842-849.

Eman Sayed Ibrahim., et al. "Comparison of Electrical Cardiometry and Transoesophageal Doppler for Haemodynamic Monitoring during Living Donor Liver Transplantation: A Randomized Controlled Trial". EC Anaesthesia 5.4 (2019): 81-91.